Zhao, Mengke
Wang, Jiayi
Zhu, Shuaiyu
Zhang, Shensen
Han, Chao
Tan, Chengcheng
Huang, Yubing
Sun, Zhaokai
Wang, Liang
Liu, Jing
Funding for this research was provided by:
Dalian Science and Technology Talent Innovation Support Policy Implementation Plan High-level Talent Team (2022RG18)
National Nature Science Foundation of China (82072953)
Dalian Outstanding Young Talents Project (2021RJ12)
Dalian Young Science and Technology Stars Talent Program (2024RQ011)
Liaoning Province Science and Technology Plan Joint Program Talent Project (2024-MSLH-116, 2024-BSLH-053)
Doctoral Scientific Startup Fund of Liaoning Province (2023-BS-159)
Article History
Received: 25 November 2024
Accepted: 20 February 2025
First Online: 5 April 2025
Declarations
:
: Human neural stem cell was obtained from the human fetal forebrain tissue of healthy pregnant women at 10–12 weeks of gestation who requested induced abortion, all of whom provided informed consent and tested negative for pathogenic microorganisms. All procedures were approved by the Clinical Research Ethics Committee of the First Affiliated Hospital of Dalian Medical University (Approved project: Clinical research of neural stem cells, Approval No. LCKY2016-60, Approval date: Dec. 2nd 2016), and complied with the standards of the National Health Research Institute. The experiments conducted on animals were approved by the Ethics Committee of the Animal Experiment Center of Dalian Medical University and performed following the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health (Approved project: Study on the repair of neurological damage in ischemic stroke by engineered neural stem cell vesicles, Approval No. AEE23127, Approval date: Feb. 28th 2023). Methods for each procedure were performed in accordance with the approved guidelines and regulations. All experiments were conducted in compliance with the ARRIVE guidelines.
: Not applicable.
: The authors declare no competing financial interest.