You, Chengyu
Fang, Qixiang
Qing, Liangliang
Xiao, Xi
Liu, Yang
Yang, Weiguang
Li, Qingchao
Li, Rongxin
Wang, Yanan
Dong, Zhilong https://orcid.org/0009-0001-8862-4445
Funding for this research was provided by:
National Natural Science Foundation of China (82160148)
Fundamental Research Funds for the Central Universities (lzujbky-2023-ct06)
Gansu Province Major Science and Technology Special Project (24ZDFA007)
Article History
Received: 7 May 2025
Accepted: 3 October 2025
First Online: 4 November 2025
Declarations
:
: This study was approved by the Ethics Committee of the Second Hospital of Lanzhou University for both human and animal experiments. Human tissue collection and related experiments were approved under Approval No. 2024 A–948, with written informed consent obtained from all patients prior to tissue collection. Animal experiments were conducted following institutional guidelines and were approved under Approval No. D2024–686.
: All patients involved in this study provided written informed consent for the use of their clinical data for research and publication purposes. The consent process included disclosure that their de–identified data may be made publicly available online and in print following publication. No identifying information (such as name, initials, date of birth, or hospital number) has been included in this manuscript. The study protocol and consent procedures were reviewed and approved by the institutional ethics committee, and all efforts were made to ensure patient confidentiality and compliance with data protection regulations.
: The authors declare no competing financial or non–financial interests.