Yan, Jiayao
Zhong, Liqing
Chen, Xiaotong
Li, Lin
Liu, Fangcen
Lei, Lei
An, Mengchao
Wei, Xiao
Wang, Ying
Chen, Tianran
Guo, Jingyi
Shao, Jie
Yu, Xiaoxiao
Zhao, Yingjie
Li, Rutian
Liu, Qin
Liu, Baorui https://orcid.org/0000-0002-2539-7732
Funding for this research was provided by:
Natural Science Foundation of China grant (82272811)
Jiangsu Provincial Medical Key Discipline grant (ZDXK202233)
Jiangsu Province Key Research and Development Program grant (BE2023654)
Article History
Received: 3 June 2025
Accepted: 14 October 2025
First Online: 20 November 2025
Declarations
:
: All human tissue samples applied in this study were obtained from Pathology Department of Nanjing Drum Tower Hospital. This study was performed in accordance with the Declaration of Helsinki. All patients included were consented to participate in the study and to use their tissue samples in research. Our study protocol was approved by the Ethics Committee of Nanjing Drum Tower Hospital. In this study, the ethics approval statements for animal work were provided by the Institutional Animal Care and Use Committee (IACUC) of Nanjing Drum Tower Hospital. The procedures for animal experiments were carried out in accordance with the Guide of Care and Use of Laboratory Animals, 8th Edition (2011). All animal experiments were carried out according to the IACUC guidelines, and all studies followed the approved protocols by the IACUC at Nanjing Drum Tower Hospital.
: All authors contributed significantly to the conception, design, execution, and interpretation of the research. They reviewed and approved the manuscript. All authors agreed to be listed as co-authors.
: All authors declare that they have no competing interests.