Funding for this research was provided by:
Guangdong Basic and Applied Basic Research Foundation (2022A1515220075)
The Scientific Research Projects of Medical and Health Institutions of Shenzhen Longhua District, Shenzhen (2022049)
Guangzhou Basic and Applied Basic Research Foundation (202201020509)
Shenzhen Science and Technology Program (JCYJ20220531092607017)
Shenzhen Science and Technology Program (JCYJ20250604184308012)
Article History
Received: 3 July 2025
Accepted: 13 November 2025
First Online: 8 December 2025
Declarations
:
: This study was approved by the Institutional Review Board (IRB) of Shenzhen Longhua District Central Hospital (2024-049-02). All patients provided written informed consent prior to participation in the study. Patient anonymity was maintained throughout the study, and all procedures were in accordance with the Declaration of Helsinki. The animal experiments were approved by the Laboratory Animal Ethics Committee of Guangdong Medical University (GDY2402433).
: Not applicable.
: The authors declare that there are no conflicts of interest.