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HDL-C and systemic inflammatory response index mediate the association between visceral adipose tissue and risk of cardiovascular disease among young and middle-aged adults with prediabetes or diabetes: a national cohort study

Crossref DOI link: https://doi.org/10.1186/s12967-025-07519-7

Published Online: 2025-12-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wu, Wanzhou

Zhang, Feng

Wen, Song https://orcid.org/0000-0002-1648-5722
Qiu, Xueting
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82400489)

Hunan Provincial Natural Science Foundation of China (2025JJ60510)

Hunan Provincial Natural Science Foundation of China (2023JJ41019)
License Information

Text and Data Mining valid from 2025-12-02

Version of Record valid from 2026-01-06
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Article History

Received: 17 June 2025

Accepted: 25 November 2025

First Online: 2 December 2025

Declarations

:

: The study protocol was approved by the National Center for Health Statistics Ethics Review Committee. All individuals provided written informed consent before participating in the study.

: Not applicable.

: The authors have no conflicts of interest to declare.

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