Funding for this research was provided by:
the National Natural Science Foundation of China (Nos. 81974469)
the National Natural Science Foundation of China (Nos. 82472835)
the National Science Foundation of China for Youths (No.82203166)
General Project of Hunan Provincial Health Commission Research Program (No. B202302057895)
the Science and Technology Innovation Program of Hunan Province (2022RC4044)
the Hunan Province Graduate Research and Innovation Project (CX20230951)
the Hunan Province Graduate Research and Innovation Project (CX20230952)
the Foundation of Hunan Provincial Key Laboratory (2023TP1014)
Interdisciplinary Research Program in Medicine and Engineering, The First Affiliated Hospital of University of South China (IRP-M&E-2025-12)
University of South China Innovation Foundation For Undergraduate (D202405201402298706)
University of South China Innovation Foundation For Undergraduate (D202405251317308759)
Article History
Received: 1 September 2025
Accepted: 29 November 2025
First Online: 11 December 2025
Declarations
:
: Not applicable.
: All authors have approved the submitted version of manuscript for publication.
: The authors declare that they have no competing interests.