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Integrative single-cell and spatial transcriptomic analysis reveals lipid metabolism–mediated macrophage heterogeneity during colorectal cancer liver metastasis progression

Crossref DOI link: https://doi.org/10.1186/s12967-025-07581-1

Published Online: 2025-12-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Qi, Xin https://orcid.org/0000-0001-9038-4287
Hou, Siyu

Xie, Shaozhuo

Chen, Jiajia
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (32270705)

Postgraduate Research & Practice Innovation Program of Jiangsu Province (SJCX24_1879)

Qinglan Project of Jiangsu Higher Education Institutions (Qinglan Project of Jiangsu Higher Education Institutions (Excellent Young Backbone Teacher Program))
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Text and Data Mining valid from 2025-12-22

Version of Record valid from 2026-01-29
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Article History

Received: 2 October 2025

Accepted: 11 December 2025

First Online: 22 December 2025

Declarations

:

: Not applicable.

: Not applicable.

: The authors declare no competing interests.

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