de Sousa, Eric https://orcid.org/0000-0001-6582-7365
Lérias, Joana R. https://orcid.org/0000-0002-9874-5259
Gorgulho, Carolina M. https://orcid.org/0000-0001-6569-8647
Chaves-Ferreira, Miguel
Balan, Vitaly
Pan, Wenjing
Byrne-Steele, Miranda
Wang, Zhe
Han, Jian
Gama-Carvalho, Margarida https://orcid.org/0000-0002-0365-6916
Maeurer, Markus https://orcid.org/0000-0002-8436-8077
Article History
Received: 17 December 2025
Accepted: 18 December 2025
First Online: 6 February 2026
Declarations
:
: The study was approved by the Champalimaud Foundation Ethics Committee (December 7th, 2021, CAN-TREAT) and was conducted in accordance with Good Clinical Practice guidelines. Dispensable tissue samples were obtained from the Champalimaud Foundation Biobank. Informed consent was obtained for study volunteers in accordance with the Declaration of Helsinki.
: Not applicable.
: WP and MB-S are employees of iRepertoire. JH is the Founder and Chairman of the board of iRepertoire. The remaining authors declare that they have no conflict of interest.