Tan, Chengbo
Zhou, Yujing
Li, Shuang
Dong, Bin
Yu, Fangjing
Bai, Changchuan
Zhang, Linli
Wang, Yue
Lou, Meiqing
Qi, Xiangqian
Wang, Xiaojie
Cui, Xiaonan https://orcid.org/0000-0001-9130-3813
Funding for this research was provided by:
National Natural Science Foundation of China (No. 81901780)
Science and Technology Commission of Shanghai Municipality (No. 20S11906000)
Article History
Received: 30 August 2025
Accepted: 22 December 2025
First Online: 29 January 2026
Declarations
:
: This study was conducted in full accordance with the following international and national ethical standards and regulatory guidelines: The Declaration of Helsinki (World Medical Association, 2024 revision); The International Ethical Guidelines for Health-related Research Involving Humans issued by CIOMS (2016); The Ethical Review Measures for Biomedical Research Involving Humans (National Health Commission of China, 2016); The Administrative Measures for Ethical Review of Life Sciences and Medical Research Involving Humans (National Health Commission of China, 2023); The Administrative Measures for Investigator-Initiated Clinical Research in Medical Institutions (National Health Commission of China, 2024). The study protocol, informed consent forms, data collection procedures, and all recruitment materials were reviewed and approved by the Ethics Committee of The First Affiliated Hospital of Dalian Medical University (Approval No. PJ-KS-KY-2025-394). Written informed consent was obtained from all participants or their legally authorized representatives prior to inclusion. All data were anonymized prior to analysis.
: The present manuscript or any data have not been published previously.
: The authors have no conflicts of interest to declare.