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Article History

Received: 2 September 2025

Accepted: 19 December 2025

First Online: 9 January 2026

Declartions

:

: The animal study protocol received approval from the Ethics Committee of Guizhou Medical University. All experimental procedures were strictly conducted in accordance with the guidelines set forth in the National Institutes of Health Guide for the Care and Use of Laboratory Animals, thus ensuring the welfare and ethical treatment of the animal subjects.

: The authors confirm that written informed consent was obtained from all participants (and/or their legal guardians/next of kin) for the publication of any potentially identifiable data or images included in this article.

: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors confirm that this statement is accurate and complete, and they are fully responsible for its content.