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Authors
Yang, Jiabin
Cao, Bingxin
Yuemaierabola, Anwaier
Gong, Yanyu
Guo, Yusheng
Zhong, Haoming
Zhang, Kailu
Wang, Sichen
Huang, Qiaozhi
Li, Jiaqing
Ye, Tao
Luo, Jianwei
Zhou, Yu
Chen, Rufu https://orcid.org/0009-0001-9442-6883
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Funding
Funding for this research was provided by:
National Key Research and Development Program of China (2023YFC2413401)
Science and Technology Program of Guangzhou, China (2024B01J1379)
Precision Diagnosis and Treatment Center for Liver, Gallbladder, and Pancreas Diseases Project of Guangdong Provincial People’s Hospital, China (KY012023453)
National Natural Science Foundation of China (82372858,82072639)
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Article History
Received: 2 December 2025
Accepted: 22 January 2026
First Online: 30 January 2026
Declarations
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: This study was conducted in accordance with the Declaration of Helsinki. Ethical approval was obtained from the UK NHS Research Ethics Committee (21/NW/0157) for the UK Biobank cohort and from the Ethics Committee of Guangdong Provincial People’s Hospital (approval number: KY2025-682-01) for the clinical validation cohort. Written informed consent was obtained from all participants involved in this study.
: This research has been conducted using the UK Biobank Resource under Application Number-85244.
: The authors declare no conflict of interest.
