Crossmark

In vitro evidence and integrative bioinformatics identify the SGLT2-PPARγ axis as a target against polyethylene microplastic-driven metabolic reprogramming in colorectal cancer cells

Crossref DOI link: https://doi.org/10.1186/s12967-026-07776-0

Published Online: 2026-02-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Donisi, Isabella

Sardu, Celestino

Colloca, Antonino

Balestrieri, Anna

Vecchio, Vitale Del

Marfella, Raffaele

Campanile, Giuseppe

D’Onofrio, Nunzia

Balestrieri, Maria Luisa
Funding

Funding for this research was provided by:

Ministero della Salute (IZS ME 09/22)

Ministero dell'Università e della Ricerca (P2022SZE5Y)

Ministero dell'Università e della Ricerca (2022KH87XS)

Ministero dello Sviluppo Economico (F/310110/04/X56)
License Information

Text and Data Mining valid from 2026-02-02

Version of Record valid from 2026-03-03
More Information

Article History

Received: 2 December 2025

Accepted: 23 January 2026

First Online: 2 February 2026

Declarations

:

: Not applicable.

: Not applicable.

: The authors declared no conflict of interest.

Document is current

Any future updates will be listed below