Yang, Yunxiao
Lan, Yuzhen
Bian, Linxi
Li, Yufei
Song, Qin
Gao, Xinmei
Hou, Qiaoyun
Bai, Yundan
Chen, Bo
Article History
Received: 9 August 2025
Accepted: 6 January 2026
First Online: 10 April 2026
Declarations
:
: The studies involving human samples were approved by Shanghai Liquan Hospital ethics committee (20212002-C221). All animal experiments were conducted in accordance with the Guide for the Care and Use of Laboratory Animals and are complied with with the ARRIVE guidelines. All animal procedures were conducted in compliance with the relevant laws and regulations on the use and management of laboratory animals and the requirements of the Animal Ethics Committee of Breath Smooth Biotech Hangzhou CO., LTD. (Application No.: BSB-AUP-23142). Cynomolgus monkey studies were performed under number A2023058-K015-01, and mouse experiments under numbers BSB231424 and BSB23136.
: Not applicable.
: Not applicable.
: Y.Y. is an intern at Keymed Biosciences (Chengdu) Limited. Q.S., X.G., and B.C. are employees of Keymed Biosciences (Chengdu) Limited. The other authors declare no conflicts of interest.