Zhai, Yunpeng
Zhao, Haiyu
Wang, Zhenya
Zhang, Yi
Zhao, Senfeng
Wang, Chongyang
Liu, Yin
Cao, Jiahui
Lin, Chaojie
Wu, Yahui
Liang, Ruopeng
Zhu, Rongtao
Wang, Weijie
Li, Jian
Sun, Yuling https://orcid.org/0000-0001-5289-4673
Funding for this research was provided by:
National Natural Science Foundation of China (82172944)
Science and Technology Innovation Talents in Universities of Henan Province (26A320033)
Article History
Received: 25 June 2026
Accepted: 13 August 2026
First Online: 28 August 2026
Declarations
Ethics approval and consent to participate: This study collected clinical hepatocellular carcinoma and paired peritumoral tissue specimens from surgical patients. The specimen collection protocol was reviewed and approved by the Ethics Committee of The First Affiliated Hospital of Zhengzhou University (Approval No. 2022-KY-1519-002). Written informed consent was obtained from all enrolled patients before specimen collection. All procedures involving human clinical samples were performed in strict accordance with the ethical principles stated in the Declaration of Helsinki. All procedures were approved by Zhengzhou University’s Institutional Animal Care and Use Committee (IACUC Approval No [ZZU-LAC2025041516]) and conducted in strict accordance with ARRIVE guidelines 2.0.
Consent for publication: No human subject images or clinical case data are presented in this manuscript, so additional publication consent is not required.
Competing interests: The authors declare no conflicts of interest.