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Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation

Crossref DOI link: https://doi.org/10.1186/s12969-020-00483-0

Published Online: 2020-11-16

Published Print: 2020-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Simonds, Megan M. http://orcid.org/0000-0002-2685-2645
Schlefman, Amanda R.

McCahan, Suzanne M.

Sullivan, Kathleen E.

Rose, Carlos D.

Brescia, AnneMarie C.
Funding

Funding for this research was provided by:

National Institutes of Health (1K23AR066724-01)

Nancy Taylor Foundation for Chronic Diseases (3205042004)
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Text and Data Mining valid from 2020-11-16

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Article History

Received: 6 May 2020

Accepted: 1 November 2020

First Online: 16 November 2020

Ethics approval and consent to participate

: Synovial fluid and synovial tissue samples were obtained from our Institutional Review Board-approved repository. Patients who underwent clinically indicated arthrocentesis were offered inclusion into the repository and informed consent was obtained.

: Not applicable.

: Not applicable.

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