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The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes

Crossref DOI link: https://doi.org/10.1186/s12969-021-00556-8

Published Online: 2021-05-12

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Simonds, Megan M. http://orcid.org/0000-0002-2685-2645
Schlefman, Amanda R.

McCahan, Suzanne M.

Sullivan, Kathleen E.

Rose, Carlos D.

Brescia, Anne Marie C.
Funding

Funding for this research was provided by:

Foundation for the National Institutes of Health (1K23AR066724)

Nancy Taylor Foundation for Chronic Diseases (3205042004)
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Article History

Received: 5 November 2020

Accepted: 16 April 2021

First Online: 12 May 2021

Declarations

:

: Synovial fluid and synovial tissue samples were obtained from our Institutional Review Board-approved repository. Patients who underwent clinically indicated arthrocentesis were offered inclusion into the repository and informed consent and assent was obtained.

: Not applicable.

: Not applicable.

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