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The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

Crossref DOI link: https://doi.org/10.1186/s12974-018-1134-4

Published Online: 2018-03-28

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Söllvander, Sofia

Nikitidou, Elisabeth

Gallasch, Linn

Zyśk, Marlena

Söderberg, Linda

Sehlin, Dag

Lannfelt, Lars

Erlandsson, Anna
Funding

Funding for this research was provided by:

Vetenskapsrådet (#2012-2172)

Alzheimerfonden

Åhlén-stiftelsen

Gun och Bertil Stohnes Stiftelse

Magnus Bergvalls Stiftelse

Demensförbundet

Petrus och Augusta Hedlunds Stiftelse

Uppsala Berzelii Center
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Text and Data Mining valid from 2018-03-28
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Article History

Received: 3 January 2018

Accepted: 19 March 2018

First Online: 28 March 2018

Ethics approval and consent to participate

: All experiments involving animals were performed at Uppsala University, Sweden. The experiments were approved by the Uppsala County Animal Ethics Board (ethical permit number: C75/13, valid 2013-06-28 to 2018-06-28), following the rules and regulations of the Swedish Animal Welfare Agency, in compliance with the European Communities Council Directive of 22 September 2010 (2010/63/EU).

: Not applicable.

: LS is employed by BioArctic AB. LL is a co-founder of BioArctic AB and stock owner. This does not alter to theJournal of Neuroinflammationpolicies on sharing data and materials. None of the authors have any financial relationship with the organizations that sponsored the research. The other authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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