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Inhibition of the hepatic Nlrp3 protects dopaminergic neurons via attenuating systemic inflammation in a MPTP/p mouse model of Parkinson’s disease

Crossref DOI link: https://doi.org/10.1186/s12974-018-1236-z

Published Online: 2018-07-02

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Qiao, Chen

Zhang, Qian

Jiang, Qingling

Zhang, Ting

Chen, Miaomiao

Fan, Yi

Ding, Jianhua

Lu, Ming

Hu, Gang
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81630099, 81773706, 81573403)

key project of Natural Science Foundation of the Higher Education Institutions of Jiangsu Province (15KJA310002)

Foundation Research Project of Jiangsu Province (BK20170564)
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Article History

Received: 10 April 2018

Accepted: 25 June 2018

First Online: 2 July 2018

Ethics approval and consent to participate

: All experiments were carried out according to the National Institutes of Health Guidelines for the Care and Use of Laboratory Animals, and all animals were treated in strict accordance with protocols approved by the Institutional Animal Care and Use Committee of Nanjing Medical University.

: Not applicable.

: The authors declare that they have no competing interests.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.