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Lipocalin 2 contributes to brain iron dysregulation but does not affect cognition, plaque load, and glial activation in the J20 Alzheimer mouse model

Crossref DOI link: https://doi.org/10.1186/s12974-018-1372-5

Published Online: 2018-11-30

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Dekens, Doortje W.

Naudé, Petrus J. W.

Keijser, Jan N.

Boerema, Ate S.

De Deyn, Peter P.

Eisel, Ulrich L. M. http://orcid.org/0000-0003-4178-0384
Funding

Funding for this research was provided by:

Internationale Stichting Alzheimer Onderzoek (#06511)

ZonMw (Deltaplan Dementie Memorabel)

Federaal Wetenschapsbeleid

Universiteit Antwerpen (Thomas Riellaerts Research Fund, University Research Fund)

Universitair Medisch Centrum Groningen (Research School of Behavioral and Cognitive Neurosciences (BCN))

Alzheimer Nederland ((WE. 13-2015-19))
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Article History

Received: 24 July 2018

Accepted: 18 November 2018

First Online: 30 November 2018

Ethics approval

: All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. All procedures performed in studies involving animals were in accordance with EU regulations (EU Directive 2010/63/EU for animal experiments), and were approved of by the ethical animal experiment committee and the animal welfare body of the University of Groningen (Groningen, The Netherlands; DEC6851A).

: Not applicable.

: The authors declare that they have no competing interests.

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