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Therapeutic blockade of HMGB1 reduces early motor deficits, but not survival in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Crossref DOI link: https://doi.org/10.1186/s12974-019-1435-2

Published Online: 2019-02-19

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lee, John D.

Liu, Ning

Levin, Samantha C.

Ottosson, Lars

Andersson, Ulf

Harris, Helena E.

Woodruff, Trent M. http://orcid.org/0000-0003-1382-911X
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Article History

Received: 16 November 2018

Accepted: 13 February 2019

First Online: 19 February 2019

Ethics approval and consent to participate

: All experimental procedures were approved by the University of Queensland Animal Ethics Committee and complied with the policies and regulations regarding animal experimentation. They were conducted in accordance with the Queensland Government Animal Research Act 2001, associated Animal Care and Protection Regulations (2002 and 2008) and the Australian Code of Practice for the Care and Use of Animals for Scientific Purposes, 8th Edition (National Health and Medical Research Council, 2013). ARRIVE guidelines have been followed in the preparation of the manuscript.

: Not applicable.

: The authors declare that they have no competing interests.

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