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Article History

Received: 5 May 2020

Accepted: 20 August 2020

First Online: 7 September 2020

Ethics approval and consent to participate

: Animal experiments, reported in line with the ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines developed in consultation with the scientific community as part of an NC3Rs initiative to improve standards of reporting the results of animal experiments, maximizing information published and minimizing unnecessary studies, were carried out on mice purchased from Janvier Elevage (Le Genest-Saint-Isle, France). The animals were hosted at the CEA animal facility and were treated in strict adherence with the European Community guidelines for laboratory animal handling and to the guidelines established by the French Council on animal care “Guide for the Care and Use of Laboratory Animals” (EEC86/609 Council Directive—Decree 2001-131). All animal experimental procedures were approved by the Animal Ethics Committee of the CEA, by the French General Directorate for Research and Innovation (project APAFIS#5973-2016070515456532v6 authorized to FB and project APAFIS#2671-2015110915123958v4 authorized to EB) and by the Butantan Institute (CEUAIB protocol number 7334170718 authorized to GP).

: Not applicable.

: The authors declare that they have no competing interests.