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Authors
Takalo, Mari
Jeskanen, Heli
Rolova, Taisia
Kervinen, Inka
Hellén, Marianna
Heikkinen, Sami
Koivisto, Hennariikka
Jokivarsi, Kimmo
Müller, Stephan A.
Koivumäki, Esa-Mikko
Mäkinen, Petra
Juopperi, Sini-Pauliina
Willman, Roosa-Maria
Sinisalo, Rosa
Hoffmann, Dorit
Jäntti, Henna
Peitz, Michael
Fließbach, Klaus
Kuulasmaa, Teemu
Natunen, Teemu
Kemppainen, Susanna
Poutiainen, Pekka
Leinonen, Ville
Malm, Tarja
Martiskainen, Henna
Ramirez, Alfredo
Haapasalo, Annakaisa
Lichtenthaler, Stefan F.
Tanila, Heikki
Haass, Christian
Rinne, Juha
Koistinaho, Jari
Hiltunen, Mikko
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Funding
Funding for this research was provided by:
Research Council of Finland (330178, 355604, 337530, 338182)
The Strategic Funding of the University of Eastern Finland
Doctoral Programme in Molecular Medicine of the University of Eastern Finland
The Strategic Neuroscience Funding of the University of Eastern Finland
Biocenter Finland
Alzheimer’s Association (ADSF-24-1284326-C, ADSF-24-1284326-C, ADSF-24-1284326-C)
Bundesministerium für Bildung und Forschung grant (01ED2007A)
Innovative Medicines Initiative 2 Joint Undertaking which receives support from the European Union’s Horizon 2020 research and innovation programme (115975)
Sigrid Juselius Foundation
JPco-fuND-2 ‘Multinational research projects on Personalized Medicine for Neurodegenerative Diseases’ (334802, 334802, 334802)
the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy within the framework of the Munich Cluster for Systems Neurology (390857198, 390857198)
Bundesministerium für Bildung und Forschung grant, ClinspectM (FKZ161L0214C)
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Article History
Received: 21 November 2024
Accepted: 19 February 2025
First Online: 5 March 2025
Declarations
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: The animals were raised and handled at the Laboratory Animal Center of the University of Eastern Finland, Kuopio, Finland. All mouse studies were carried out in accordance with the guidelines of the European Community Council Directives 86/609/EEC and approved by the Regional State Administrative Agency and Project Authorization Board (ESAVI/7315/2024, EKS-004–2019). All study protocols concerning human samples were approved by the Medical Research Ethics Committee of Wellbeing Services County of North Savo (formerly the Medical Research Ethics Committee of North Savo Hospital District, 833/2023, 123/2016). Participant recontacting was approved by the Scientific Steering Committee of Auria Biobank (BB_2020-0062).
: All the authors have approved the final version of the manuscript and provided their consent for publication.
: CH collaborates with Denali Therapeutics and is a member of the advisory boards of AviadoBio and Cure Ventures.
