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Article History

Received: 25 November 2024

Accepted: 5 June 2025

First Online: 30 June 2025

Declarations

:

: The NNTC studies were conducted in accordance with human subject protection protocols with written consent obtained at the collection sites. Participants were enrolled at any of 4 NNTC clinical sites located in Galveston TX, Los Angeles CA, New York City NY, and San Diego CA. Enrollment and collection of specimens was performed under the oversight of each medical center’s local Institutional Review Board. All participants consented to the use of their data for the purposes of HIV and neuroAIDS/neuroHIV research with all informed consent procedures including tests of comprehension to ensure cognitively impaired participants were able to consent. Criteria for enrollment of individuals in the study includes willingness to be an organ donor upon demise. The following offices maintained the IRBs that performed oversight for the protection of human subjects: University of Texas Medical Branch Office of Research Subject Protections, Galveston, TX; University of California, San Diego, Human Research Protections Program, San Diego, CA; University of California, Los Angeles, Office of Human Research Protection Program, Los Angeles, CA; Mount Sinai Medical Center, Program for Protection of Human Subjects, New York, NY.All procedures involving animals were performed in accordance with the National Institute of Health Guide for the Care and Use of Laboratory Animals and approved by the Institutional Animal Care and Use Committees of the Sanford-Burnham-Prebys Medical Discovery Institute, The Scripps Research Institute and the University of California, Riverside.

: N/A.

: The authors declare no competing interests.