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Authors
Hyvärinen, Tanja
Tilvis, Johanna
Giudice, Luca
Tujula, Iisa
Nylund, Marjo
Ohtonen, Sohvi
Scoyni, Flavia
Jäntti, Henna
Virtanen, Lassi
Pihlava, Sara
Kattelus, Roosa
Skottman, Heli
Narkilahti, Susanna
Airas, Laura
Malm, Tarja
Hagman, Sanna
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Funding
Funding for this research was provided by:
Tampere University
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Article History
Received: 16 April 2025
Accepted: 28 September 2025
First Online: 31 October 2025
Declarations
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: The study concerning MRI and PET imaging of healthy controls and patients was approved by the Ethics Committee of the Hospital District of Southwest Finland (Dnro: 48/1801/2019). Written informed consent was obtained from all participants according to the principles of the Declaration of Helsinki. Procedures concerning production of MS patient-derived iPSC lines (48/1801/2019) were approved by the Ethics Committee of the Hospital District of Southwest Finland. Supportive ethical statements for human iPSC control lines (R08070, R12123), and for culturing and differentiating iPSCs for neuronal research (R20159) were obtained from the Wellbeing Services County of Pirkanmaa. Informed consent was obtained from all the subjects.
: Not applicable.
: The authors declare no competing interests.
