Chen, Yun
Jiang, Lingling
Yao, Dongxiao
Liu, Dandan
Pan, Yuesong
Wang, Yilong
Funding for this research was provided by:
The National Natural Science Foundation of China (82425101)
Beijing Municipal Science and Technology Commission, Adminitrative Commission of Zhongguancun Science Park (Z231100004823036)
Capital’ Funds for Health Improvement and Research (2022-2-2045)
Key Technologies Research and Development Program (2024YFC3044800, 2022YFF1501500, 2022YFF1501501, 2022YFF1501502, 2022YFF1501503, 2022YFF1501504, and 2022YFF1501505)
Article History
Received: 11 September 2025
Accepted: 30 December 2025
First Online: 21 January 2026
Declarations
:
: The protocol of the CNSR-III study was approved by ethics committee at Beijing Tiantan Hospital (IRB approval number: KY2015-001-01) and all participating centres. The protocol of the PRECISE study was approved by ethics committee at Beijing Tiantan Hospital (IRB approval number: KY2017-010-01) and lishui hospital (IRB approved number: 2016-42).
: All authors have approved this manuscript.
: The authors declare no competing interests.