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Immune imbalance between T helper 1, T helper 17 and regulatory T cells fuels amyotrophic lateral sclerosis pathogenesis: disease trajectory, diagnosis and therapeutic implications

Crossref DOI link: https://doi.org/10.1186/s12974-026-03764-9

Published Online: 2026-03-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sligar, Chloe https://orcid.org/0000-0002-9214-0742
Sluyter, Ronald https://orcid.org/0000-0003-4909-686X
Ooi, Lezanne https://orcid.org/0000-0001-9241-8268
Funding

Funding for this research was provided by:

U.S. Department of Defense (AL210095)

Australian Research Council Centre of Excellence in Quantum Biotechnology (CE230100021)
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Text and Data Mining valid from 2026-03-12

Version of Record valid from 2026-04-20
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Article History

Received: 21 November 2025

Accepted: 4 March 2026

First Online: 12 March 2026

Declarations

:

: Not applicable.

: Not applicable.

: The authors declare no competing interests.

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