Crossmark

Activation of the NR3C1–STAT3–SLC6A2 signaling axis by a cyanidin-3-O-glucoside–enriched anthocyanin preparation attenuates neuroinflammation and pain hypersensitivity in intervertebral disc degeneration

Crossref DOI link: https://doi.org/10.1186/s12974-026-03791-6

Published Online: 2026-04-07

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Xue, Bao

Qiu, Gao-Lin

He, Peng

Chen, Ruo-Fei

Duan, Wei

Gao, Lu

Chen, Long

Wang, Cun-Zhi

Yu, Tian-Hang

Chen, Chun-Lei

Tang, Wen-Ping

Shi, Ting-Ting

Mao, Wen-Bao

Wang, Hui

Hong, Yang

Feng, Shi

Shi, Xiao-Yu

Ding, Fang-Fang

Ke, Jing

Wang, Yuan

Zhuang, Li

Luan, Qian-Qian

Xu, Wan-Yan

Wang, Li-Na

Xu, Jia-Feng

Tu, You-Lin

Chen, Guan-Jun

Cai, Hua-Bao

Wang, Xian-Xiang

Cai, Qiang
Funding

Funding for this research was provided by:

Anhui Provincial Department of Education (YJS20230074)
License Information

Text and Data Mining valid from 2026-04-07

Version of Record valid from 2026-05-27
More Information

Article History

Received: 1 December 2025

Accepted: 25 March 2026

First Online: 7 April 2026

Declarations

:

: The authors declare no competing interests.

Document is current

Any future updates will be listed below