He, Zhicheng
Xing, Yihui
Gu, Jianqi
Xu, Daxiang
He, Peixuan
Lin, Xiaoqian
Cui, Wenjing
Lv, Huiling
Ding, Haoxuan
Sui, Kai
Hao, Wenting
Zheng, Yutao
Yang, Xiaoying
Huang, Xufeng
Yin, Kun
He, Cheng
Zheng, Kuiyang
Yu, Yinghua https://orcid.org/0000-0003-2508-7512
Pan, Wei
Funding for this research was provided by:
Training Programs of Innovation and Entrepreneurship for College Students in Jiangsu Province (202410313045Y)
the Training Programs of Innovation and Entrepreneurship for College Students in Jiangsu Province (202510313019)
National Natural Science Foundation of China (No. 82302557)
Open competition Grant of Xuzhou Medical University
Natural Science Foundation of Jiangsu Province (No. BK20201459)
the XZHMU-QL Joint Research Fund (No. QL-YB022)
the 333 High-level Talent Training Project of Jiangsu Province
Article History
Received: 5 December 2025
Accepted: 21 April 2026
First Online: 29 April 2026
Declarations
:
: Ethics statement All animal experiments were carried out in strict accordance with the Guide for the Care and Use of Laboratory Animals of the Ministry of Health (China), and approved by the Ethics Committee of Xuzhou Medical University (Xuzhou, China, SYXK (Su) 2020-0048). Human experimentation involved in the study was performed under the International Guiding Principles for Biomedical Research Involving Animals, as issued by the Council for the International Organizations of Medical Sciences and the guidelines set by the Institutional Animal Care and Use Committee of Shandong First Medical University (Approval number: R2021030053).
: The authors declare no competing interests.