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Authors
Wu, Xiaoyu
Zhou, Kegui
Wang, Cong
Zhang, Yi
Chen, Jiamin
Milner, Richard https://orcid.org/0000-0002-3327-3609
Dai, Jiapei https://orcid.org/0000-0002-1474-5754
Li, Longxuan https://orcid.org/0000-0001-7975-2667
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (No. 82371465, 82571675, 82171462)
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Article History
Received: 6 April 2026
Accepted: 23 July 2026
First Online: 30 July 2026
Declarations
Ethics approval and consent to participate: The study was conducted in accordance with the principles of the Helsinki Declaration and approved by the local ethics committee (2024-83). All participants provided written informed consent prior to enrollment. For animal studies, all procedures strictly adhered to the National Institutes of Health (NIH) Guidelines for the Care and Use of Laboratory Animals and were approved by the Institutional Animal Care and Use Committee (IACUC) of Xinhua Hospital. Regarding human tissue samples, permission for brain autopsy and use of the brain material and medical records for research purposes were obtained in accordance with the CBBC and the human body donation program. Appropriate consent was secured either from the donors themselves or from relatives and were also approved by the Biomedical Research Ethics Committee of South-Central Minzu University (no.2024-scuec-046).
Consent for publication: All authors have read the final version of the manuscript and approved it for publication.
Competing interests: The authors declare no competing interests.
