Document is current
Any future updates will be listed below
-
Authors
Sbriscia, Matilde
Fantone, Sonia
Di Rosa, Mirko
Marchegiani, Francesca
Recchioni, Rina
Matacchione, Giulia
Giordani, Chiara
Piacenza, Francesco
Giacconi, Robertina
Gentilini, Davide
Calzari, Luciano
Fortunato, Carlo
Badillo Pazmay, Gretta Veronica
Cecati, Monia
Caccese, Sara
Francini, Emanuele
Maniscalco, Rosanna
Cardelli, Maurizio
Tortato, Elena
Lenci, Federica
Rosati, Yuri
Burattini, Maurizio
Antonicelli, Roberto
Corsonello, Andrea
Soraci, Luca
Biscetti, Leonardo
Fedecostante, Massimiliano
Sarzani, Riccardo
Malavolta, Marco
Casoli, Tiziana
Conte, Maria
Di Valerio, Silvia
Giuliani, Angelica
Procopio, Antonio Domenico
Lattanzio, Fabrizia
Bonfigli, Anna Rita
Cherubini, Antonio
Franceschi, Claudio
Sabbatinelli, Jacopo https://orcid.org/0000-0001-9947-6778
Olivieri, Fabiola
-
Funding
Funding for this research was provided by:
European Commission (Project Age-It: “Ageing Well in an Ageing Society”)
European Commission (PNRR-MAD-2022–12376806)
- License Information
-
More Information
Article History
Received: 6 November 2025
Accepted: 14 December 2025
First Online: 19 December 2025
Declarations
:
: This study was conducted in accordance with the Declaration of Helsinki and approved by the relevant local ethics committees of the IRCCS INRCA network. All participants provided written informed consent prior to enrollment. The study was part of the ReportAGE project (ClinicalTrials.gov Identifier: NCT01397682), an ongoing epidemiological cohort investigating health outcomes in hospitalized older adults. For the subset of patients undergoing epigenetic analyses, the study protocol was approved by the Ethics Committee of the Italian National Research Center on Aging (CE INRCA 20031, 04/02/2021). Only patients able to provide informed consent were enrolled, in accordance with ethical requirements, which may have led to underrepresentation of individuals with severe cognitive impairment, advanced dementia, or impaired consciousness at admission. Data collection and processing were carried out following Good Clinical Practice guidelines and applicable national regulations.
: Not applicable.
: The authors declare no competing interests.
