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Authors
Sugihara, Yoshihiko
Ushida, Yusuke
Fukushima, Yuko
Nozawa, Hajime
Tsuji, Ryohei
Fujiwara, Daisuke
Kawakami, Ayuka
Tomida, Kouki
Shimada, Hiroyuki
Maruyama, Mitsuo
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Funding
Funding for this research was provided by:
the National Center for Geriatrics and Gerontology of Japan (21-2, 24-9)
Japan Society for the Promotion of Science (22H03524)
Kirin Holdings Co., Ltd. (AL00051783, AL00011503)
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Article History
Received: 29 September 2025
Accepted: 6 January 2026
First Online: 19 January 2026
Declarations
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: The study was conducted in accordance with the Declaration of Helsinki, and approved by the Ethics and Conflict of Interest Committee, National Center for Geriatrics and Gerontology (approval number: 1716-3). The protocol was registered in University Hospital Medical Information Network Clinical Trial Registry as UMIN000052244. Written informed consent was obtained from the participants.
: Not applicable.
: The authors declare no competing interests.
