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Authors
Li, Jichen
Duan, Wei
Liu, Ying
Wang, Rui
Yang, Qian
Li, Huijie
Liang, Yucai
Xiao, Jinbo
Zhou, Jianfang
Sun, Qiang
Zhang, Yong
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Funding
Funding for this research was provided by:
National Disease Control and Prevention Administration Public Health Talent Training Support Project (GJJKJ-2024-ZY)
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID) grant (ZDGWNLJS25-36)
National Key Research and Development Program of China (2021YFC2302003)
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Article History
Received: 12 May 2025
Accepted: 30 September 2025
First Online: 29 October 2025
Declarations
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: All experiments involving mice were approved by the Second Ethics Review Committee of the National Institute for Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention (approval no. 20221012098). Animal care and maintenance adhered to the guidelines outlined in the Regulations for the Administration of Affairs Concerning Experimental Animals, issued by the Ministry of Science and Technology of China. All mice were housed under specific-pathogen-free (SPF) conditions in individually ventilated cages equipped with irradiated bedding, food, and reverse-osmosis-purified water. B6-Ifnar1 em9 (IFNAR -/- , 14008 A) and B6/JGpt-Fcgrt em1Cin(hFCGRT) /Gpt (hFcRn, T006214) strains were obtained from GemPharmatech Co., Ltd. hFcRn-IFNAR -/- mice were generated, which were deficient in mouse FcRn and IFNAR and homozygous for the hFcRn transgene.
: The authors declare no competing interests.
