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Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice

Crossref DOI link: https://doi.org/10.1186/s12987-023-00434-3

Published Online: 2023-05-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Gao, Ling

Peng, Li

Sherchan, Prativa

Tang, Hong

Liu, Yu

Xiao, Jie

Shi, Hui

Luo, Yujie

Tang, Jiping

Zhang, John H.

Xia, Ying
Funding

Funding for this research was provided by:

Natural Science Foundation of Hainan Province (No.822MS205, NO.821QN1005)

Scientific Research Projects of Hainan Provincial Health and Family Planning Industry (No.21A200327)

National Institutes of Health (NS081740)

Hainan Province Clinical Medical research Center (No.LCYX202107)
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Article History

Received: 21 February 2023

Accepted: 25 April 2023

First Online: 10 May 2023

Declarations

:

: All animal experiments were approved by the Institutional Animal Care and Use Committee at Loma Linda University. The study followed the Health’s Guide for the Care and Use of Laboratory Animals (National Research Council) and complied with the ARRIVE guidelines for reporting in vivo experiments.

: Not applicable.

: The authors declare that they have no competing interests.

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