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Article History

Received: 21 February 2022

Accepted: 6 July 2023

First Online: 13 July 2023

Declarations

:

: All animal experiments were performed in accordance with the guidelines of European legislation (Council Directive 2010/63/UE) and French Decree 2013-118 on the protection of animals used for scientific purposes and were approved by the Local Animal Care and Use Committee (TOXCOM-0236) of Occitanie Toulouse (agreement CEEA-86). The animal facilities at INRAe Toxalim are licenced by the relevant local authorities for rodents (agreement C31 555 13).

: All authors read and approved the final manuscript.

: MA and LK are co-founders of Preditox SAS, a company specialised in genotoxicity prediction. LK is CEO and MA serves as consultant to Preditox SAS. The authors declare that they have no competing interests.