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Article History

Received: 24 May 2018

Accepted: 30 July 2018

First Online: 17 August 2018

Authors’ information

: All authors were employees of Beijing Health Guard Biotechnology Co., Ltd. when this study was conducted.

: The experimental animals (BALB/c mice) were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd. (Beijing, China), and fed in the animal facility of Beijing Biocytogen Co., Ltd.. The manipulation and vaccination on the animals were strictly referred to the guideline and compliant with the regulation, which was provided by Beijing Biocytogen Co., Ltd.. Prior to the implementation, the experiment schemes and protocols were reviewed by Beijing Municipal Science and Technology Commission Administration Office of Laboratory Animals, and approved by Beijing Municipal Science and Technology Commission Laboratory Animal Management Ethics Committee (no reference number was given). During the experiments, all animals were well-fed and monitored twice per day.

: Not applicable.

: All authors were employees of Beijing Health Guard Biotechnology Co., Ltd. when this study was conducted, and potentially own stock or hold stock options in the Company. YZ, DR, HZ, and YL hold a relevant patent.

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