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Article History

Received: 23 July 2025

Accepted: 10 October 2025

First Online: 18 November 2025

Declarations

:

: This study was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. Ethical approval was obtained from the Institutional Review Board of Zhongshan Torch Development Zone People's Hospital (Ethics Committee approval number: ZTPH-2020-IRB-045) prior to study initiation. All participants provided written informed consent after receiving comprehensive explanation of the study objectives, procedures, potential risks, and benefits. The study protocol was registered and approved before patient enrollment commenced.

: Not applicable.

: The authors declare that they have no competing interests. No financial or non-financial relationships exist that could be construed as potential conflicts of interest regarding the publication of this article.

: Not applicable.