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A top–down neural circuit for affective-motivational responses of pain relief induced by electroacupuncture

Crossref DOI link: https://doi.org/10.1186/s13020-026-01349-5

Published Online: 2026-03-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Liu, Hui

Jia, Xin

Huang, Zouqin

Xia, Yong

Rong, Jun

Chen, Meiyu

Wang, Can

Qin, Chuan

Lu, Jiaqi

Li, Qiuyong

Shen, Xueyong

Zhang, Ling

Liu, Sheng
Funding

Funding for this research was provided by:

Famous Traditional Chinese Medicine Studio Construction Project of Shanghai Pudong New Area Health Commission (PDZY-2025-0707)

New Quality Clinical Specialty Program of High-end Medical Disciplinary Construction in Shanghai Pudong New Area (2025-PWXZ-17)

National Natural Science Foundation of China (32271058)

National Natural Science Foundation of China (81873379)

Shanghai Natural Science Foundation (24ZR1466300)

Shanghai Key Laboratory of acupuncture mechanism and acupoint function (21DZ2271800)
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Text and Data Mining valid from 2026-03-01

Version of Record valid from 2026-03-01
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Article History

Received: 25 September 2025

Accepted: 6 February 2026

First Online: 1 March 2026

Declarations

:

: All experiments were approved by the Institutional Animal Care and Use Committee and the Animal Ethics Committee of Shanghai University of Traditional Chinese Medicine (SZY 201710008). The protocol of clinical observation was approved by the ethical committee of the Center of Zhejiang Integrated Traditional and Western Medicine Hospital (ITWMH, No. 202101) and was registered on (Identifier: ChiCTR1800020029). All participants gave written informed consent before the study procedures.

: Not applicable.

: The authors declare no competing interests.

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