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Article History

Received: 5 February 2018

Accepted: 26 June 2018

First Online: 11 July 2018

Ethics approval and consent to participate

: Not applicable.

: Not applicable.

: Drs. María Torres-Durán, Silvia Castillo, Amparo Escribano, María Mercedes Navarro García, Daniel Pellicer, Lucía Bañuls, Francisco Casas and Francisco Dasí report no disclosures.Dr. José Luis López-Campos reports personal fees and non-financial support from Grifols, during the conduct of the study.Dr. Miriam Barrecheguren reports personal fees from Menarini, personal fees from GlaxoSmithKline, personal fees from Gebro pharme, personal fees from Novartis, personal fees from Grifols, outside the submitted work.Dr. Miravitlles reports personal fees from Boehringer Ingelheim, AstraZeneca, Chiesi, GlaxoSmithKline, Menarini, Teva, Grifols and Novartis, personal fees from Bayer Schering, Boehringer Ingelheim, GlaxoSmithKline, Gebro Pharma, CLS Behring, Cipla, MediImmune, Mereo Biopharma, Teva, Novartis and Grifols, outside the submitted work.Dr. Martinez-Delgado reports grants from Ministerio de Economía y Competitividad. ISCIII. (Spain), other from Registro Español de pacientes con Deficit de alfa-1 antitripsina (REDAAT). Fundación Española de Pulmón, during the conduct of the study.Dr. Baloira reports personal fees and non-financial support from GRIFOLS during the conduct of the study.

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