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Authors
Margutti, Ana Vitoria Barban https://orcid.org/0000-0003-2163-4523
Silva, Wilson Araújo Jr. https://orcid.org/0000-0001-9364-2886
Garcia, Daniel Fantozzi https://orcid.org/0000-0002-1243-424X
de Molfetta, Greice Andreotti https://orcid.org/0000-0003-0946-5704
Marques, Adriana Aparecida https://orcid.org/0000-0002-7549-8574
Amorim, Tatiana https://orcid.org/0000-0002-0371-9104
Prazeres, Vânia Mesquita Gadelha https://orcid.org/0000-0001-9531-1706
Boy da Silva, Raquel Tavares https://orcid.org/0000-0001-6432-4870
Miura, Irene Kazue https://orcid.org/0000-0001-9400-6697
Seda Neto, João https://orcid.org/0000-0003-2267-5386
Santos, Emerson de Santana https://orcid.org/0000-0002-9175-2210
Santos, Mara Lúcia Schmitz Ferreira https://orcid.org/0000-0002-5253-988X
Lourenço, Charles Marques https://orcid.org/0000-0002-2296-6098
Tonon, Tássia https://orcid.org/0000-0001-8504-7526
Sperb-Ludwig, Fernanda https://orcid.org/0000-0002-2460-7064
de Souza, Carolina Fischinger Moura https://orcid.org/0000-0002-7280-6260
Schwartz, Ida Vanessa Döederlein https://orcid.org/0000-0002-7933-6687
Camelo, José Simon Jr. https://orcid.org/0000-0002-4555-7633
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Funding
Funding for this research was provided by:
Nucleus of Research Support
Center for Integrative Systems Biology of University of São Paulo- Brazil
Conselho Nacional de Desenvolvimento Científico e Tecnológico
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Article History
Received: 18 November 2019
Accepted: 15 October 2020
First Online: 1 November 2020
Ethics approval and consent to participate
: The research was approved by the Scientific Committee and Research Ethics Committee of the Clinics Hospital of Porto Alegre, the main center and headquarter of the MSUD Network, Brazilian Network for Assistance and Research in Maple Syrup Urine Disease, under reference number CAEE 19061113.9.0000.5327 (20 May 2015), according to the Declaration of Helsinki. All other centers gave their ethical approval as participant centers. All patients completed an informed consent form (ICF) signed by the person in charge and their clinical data was recorded in a standardized form, filled out by the doctor responsible for the patient in his/her reference clinical center; these clinics were located in several regions of Brazil.
: Not applicable.
: The authors declare that they have no competing interests.
