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Authors
Wang, Xue
Jiang, Huizhen
Huang, Ziyang
Dong, Chao
Zhu, Weiguo
Zhang, Shuyang
Zhi, Yuxiang https://orcid.org/0000-0001-7539-6650
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Funding
Funding for this research was provided by:
National High Level Hospital Clinical Research Funding (2022-PUMCH-B-090)
CAMS Innovation Fund for Medical Sciences (2021-I2M-1-056)
National Natural Science Fund (82271815)
Beijing Natural Science Foundation -Haidian Original Innovation Joint Fund (L222082)
the National Key Research and Development Program of China (No. 2016YFC0901501)
the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (No. 2023-JKCS-02)
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Article History
Received: 24 July 2024
Accepted: 23 June 2025
First Online: 28 July 2025
Declarations
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: All participants provided informed consent under a research protocol approved by the Research Ethical Committee of the Peking Union Medical College Hospital (Approval number: K3640). Additionally, all participants gave consent for the publication of their data. No previously published graphic or tabular material has been used in this manuscript..
: All authors reviewed the final version of the manuscript and provided written agreement for its publication in Orphanet Journal of Rare Diseases as an open-access article. Additionally, all participants provided informed consent for the publication of their data.
: The authors declare that they have no competing interests.
: Our manuscript is original, has not been published before, is not currently being considered for publication elsewhere, and has not been posted to a preprint server.
