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Authors
Lucas, Amanda https://orcid.org/0009-0003-1786-370X
Zhou, Shengfan https://orcid.org/0009-0002-7150-2983
Hernandez, Lynne https://orcid.org/0009-0005-5786-0233
Bell, Timothy https://orcid.org/0000-0001-8909-5293
Oton, Ana B. https://orcid.org/0000-0002-6126-7353
Mercier, Kelly https://orcid.org/0000-0002-8771-6401
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Funding
Funding for this research was provided by:
Springworks Therapeutics (Springworks Therapeutics)
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Article History
Received: 30 September 2024
Accepted: 26 August 2025
First Online: 14 October 2025
Declarations
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: Ethical oversight and approval for the DTRF NHS was obtained from the North Star Review Board (NB100030). The DTRF NHS study was conducted in accordance with Good Clinical Practices, following guidance from ICH GCP and the United States CFR. The study was also performed in accordance with the Helsinki Declaration of 1964 and its later amendments. Informed consent was obtained electronically as part of the DTRF NHS registration process.
: Not applicable.
: AL, LH, and KM are employees of DTRF and received a grant from SpringWorks Therapeutics to support this project. TB, SZ, and AO are employees of SpringWorks Therapeutics.
