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Impaired mitochondrial morphology and respiratory dysfunction in human induced pluripotent stem cells with mitochondrial tRNA mutations (m.3243A>G and m.14739G>A)

Crossref DOI link: https://doi.org/10.1186/s13023-026-04201-z

Published Online: 2026-01-29

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Meshrkey, Fibi

Scheulin, Kelly M.

Saikia, Bibhuti

Stabach, Joshua

Rao, Raj R.

West, Franklin D.

Iyer, Shilpa https://orcid.org/0000-0001-6287-2232
Funding

Funding for this research was provided by:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (1R01HD110536-01A1)

U.S. Department of Defense (W81XWH-16-1-0181)
License Information

Text and Data Mining valid from 2026-01-29

Version of Record valid from 2026-02-20
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Article History

Received: 26 September 2025

Accepted: 7 January 2026

First Online: 29 January 2026

Declarations

:

: The current study was conducted with the approval of the University Of Arkansas Office Of Research Compliance, which determined that the project was exempt from Institutional Review Board (IRB) oversight and human research subjects protection regulations.

: Not applicable.

: The authors have declared that no competing interests exist.

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