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Authors
Heliö, Krista https://orcid.org/0000-0001-6244-1969
Ahokas, Aurelia
Sulkava, Sonja
Mäyränpää, Mikko I.
Aalto-Setälä, Katriina
Weckström, Sini
Euro, Liliya
Koskenvuo, Juha
Suomalainen, Anu
Heliö, Tiina
Ojala, Tiina
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Funding
Funding for this research was provided by:
University of Helsinki
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Article History
Received: 4 March 2026
Accepted: 23 July 2026
First Online: 13 August 2026
Declarations
Ethics approval and consent to participate: This study has been approved by the Ethical Review Committee of The Department of Medicine, University of Helsinki (HUS/144/2020, HUS/2675/2019, HUS/1187/2019, HUS/60/2019, HUS/256/2023). Statistics Finland (Dnro TK-53-345-17), Finnish Institute for Health and Welfare, and the Ministry of Social Affairs and Health have given the permission to obtain clinical data from deceased patients for research purposes (THL/1078/5.05.00/2020). This study complies with the Declaration of Helsinki.
Consent for publication: Of all participants over the age of 18, written informed consent for publication of clinical details was obtained.
Competing interests: J.K. is a cofounder, previous shareholder, and current full-time employee of Blueprint Genetics, which offers genetic diagnostic services. The remaining authors have nothing to disclose.
