Ziff, Oliver J. https://orcid.org/0000-0002-1504-7245
Parfitt, Gustavo Morrone https://orcid.org/0000-0003-0168-4099
Jolly, Sarah https://orcid.org/0000-0003-1297-0058
Casey, Jackie M. https://orcid.org/0000-0002-1447-8377
Granat, Lucy https://orcid.org/0000-0002-2767-9880
Samra, Satinder
Setó-Salvia, Núria https://orcid.org/0000-0002-3753-0027
Alatza, Argyro https://orcid.org/0000-0002-3342-6804
Phadke, Leela
Galet, Benjamin https://orcid.org/0000-0002-3857-2886
Ravassard, Philippe https://orcid.org/0000-0002-0393-9262
Potier, Marie-Claude https://orcid.org/0000-0003-2462-7150
Hardy, John https://orcid.org/0000-0002-3122-0423
Salih, Dervis A. https://orcid.org/0000-0001-7651-8998
Whiting, Paul https://orcid.org/0000-0002-4121-1379
Ducotterd, Fiona https://orcid.org/0009-0000-6064-9088
Patani, Rickie https://orcid.org/0000-0002-3825-7675
Wray, Selina https://orcid.org/0000-0003-3062-7050
Arber, Charles https://orcid.org/0000-0002-9743-8134
Funding for this research was provided by:
Alzheimer Society (AS- JF- 18- 008)
Alzheimer's Research Trust (ARUKSRF- 2016B)
UK Dementia Research Institute (UK Dementia Research Institute)
UCLH Biomedical Research Centre (UCLH Biomedical Research Centre)
Medical Research Council (MR/M02492X/1)
Article History
Received: 26 September 2024
Accepted: 12 June 2025
First Online: 20 June 2025
Declarations
:
: iPSCs were reprogrammed from fibroblasts prior to this study. Experiments were carried out according to approved regulations and guidelines from the National Hospital for Neurology and Neurosurgery and the Institute of Neurology Joint Research Ethics Committee (09/H0716/64) with informed consent.
: Not applicable.
: JH consults for Eisai and Eli Lily. These conflicts have no bearing on this study.