Duggan, Michael R.
Oh, Hamilton Se-Hwee
Frank, Philipp
Gomez, Gabriela T.
Zweibaum, David
Cui, Yuhan
Chen, Jingsha
Surapaneni, Aditya
Blew, Cassandra O.
Dark, Heather E.
Joynes, Cassandra M.
Kandala, Sridhar
Bilgel, Murat
Farinas, Amelia
Erus, Guray
Tian, Qu
Candia, Julián
Pucha, Krishna A.
Landman, Bennett A.
Dumitrescu, Logan
Hohman, Timothy J.
Lewis, Alexandria
Moghekar, Abhay
Siavoshi, Fatemeh
Ali, Muhammad
Liu, Menghan
Xu, Ying
Western, Daniel
Kaneko, Naoto
Kato, Shintaro
Furuichi, Makio
Shibayama, Masaki
Katsuno, Masahisa
Nishita, Yukiko
Otsuka, Rei
Gottesman, Rebecca F.
Dammer, Eric B.
Seyfried, Nicholas T.
Levey, Allan I.
B. Johnson, Erik C.
Mormino, Elizabeth
Wagner, Anthony D.
Poston, Kathleen L.
Kapogiannis, Dimitrios
Grams, Morgan E.
Bhargava, Pavan
Waga, Iwao
Davatzikos, Christos
Resnick, Susan M.
Ferrucci, Luigi
Bennett, David A.
Cruchaga, Carlos
Wyss-Coray, Tony
Kivimäki, Mika
Coresh, Josef
Walker, Keenan A.
Funding for this research was provided by:
National Institute on Aging
Article History
Received: 6 June 2025
Accepted: 24 December 2025
First Online: 5 January 2026
Declaration
:
: All participants provided written informed consent in accordance with the Declaration of Helsinki and protocols were approved by ethical bodies at respective institutions. Study-specific ethical statements are available in the Supplementary Methods.
: KAW is an Associate Editor at Alzheimer’s & Dementia, a member of the Editorial Board of Annals of Clinical and Translational Neurology, and on the Board of Directors of the National Academy of Neuropsychology. NK, SK, MF, MS, and IW are current employees of NEC Solution Innovators Limited and/or FonesLife Corporation. CC has received research support from GSK and EISAI. CC is a member of the scientific advisory board of Circular Genomics and owns stocks. CC is a member of the scientific advisory board of ADmit. JC was part of the SomaLogic scientific advisory board from 2021 to 2023. The remaining authors declare no competing interests..