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Authors
Jansons, Juris
Avdoshina, Daria
Dudorova, Alesja
Rubio, Elena Royo
Sokolovska, Liba
Perminov, Dmitry
Lindenberga, Ilze
Nicolai, Hannes
Gebrila, Svetlana
Chowdhury, Sona
Skrastina, Dace
Nazarovs, Jurijs
Palefsky, Joel M.
Isaguliants, Maria
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Funding
Funding for this research was provided by:
-Project of the Latvian Science Fund “Human papillomavirus genome associated correlates of disease progression and treatment response for cervical neoplasms and cancer” (LZP-2021/1-0484, LZP-2021/1-0484, LZP-2021/1-0484, LZP-2021/1-0484, LZP-2021/1-0484, LZP-2021/1-0484)
Narodowa Agencja Wymiany Akademickiej (PPI/APM/2018/1/00007/U001, PPI/APM/2018/1/00007/U001, PPI/APM/2018/1/00007/U001)
ERASMUS Internship ("Erasmus+ Programm über die Universität Hamburg")
National Institutes of Health (NIHR01CA217715, NIHR01CA217715)
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Article History
Received: 28 March 2025
Accepted: 2 July 2025
First Online: 26 July 2025
Declarations
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: A retrospective study of HR HPVs in the cervical tissues of women with high grade cervical lesions and cervical carcinomas diagnosed at the Paul Stradins University hospital was performed according to the ethical permit issued by the Ethical Committee of the Riga Stradins University N2-PĒK-4/415/2022 dated September 26, 2022. Informed consents to use biological materials in biomedical research were given by patients at the time of sampling. Experiments in the laboratory mice were carried out in compliance with the bioethical principles adopted by the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (Strasbourg, 1986). Experimental procedures were approved by the Ethical Committee of the Latvian Food and Veterinary service (protocol nr 1.1–13/18/953), permit No 99 dated June 1, 2018, valid 01.06.2018–25.05.2023.
: Manuscript does not contain any individual person’s data in any form, such as individual details, images or videos, and does not require consent for publication.
: Co-authors of this manuscript Dmitry Perminov and Ilze Lindenberga are employees of the E. Gulbja Laboratorija, Riga, Latvia, and performed analysis of the anonymized/blinded DNA samples according to the subcontract of Riga Stradins University, Riga, Latvia, financed by the project of the Latvian Science Fund 2021/1-0484. Maria Isaguliants is a member of the Editorial Board of “Infectious Agents and Cancer”. Other authors declare no conflict of interest.
