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Authors
Donà, Maria Gabriella
Giuliani, Eugenia
Laquintana, Valentina
Covello, Renato
Pellini, Raul
Moretto, Silvia
Latini, Alessandra
Benevolo, Maria
Rollo, Francesca
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Funding
Funding for this research was provided by:
Italian Ministry of Health (Ricerca corrente, Ricerca corrente, Ricerca corrente, Ricerca corrente, Ricerca corrente, Ricerca corrente, Ricerca corrente, Ricerca corrente, Ricerca corrente)
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Article History
Received: 30 May 2025
Accepted: 29 August 2025
First Online: 15 October 2025
Declarations
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: The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Comitato Etico Territoriale Lazio Area 5 (IFO/51/23, 25 Oct 2023). The Ethics Committee also granted exemption from informed consent.
: Francesca Rollo has received financial and non-financial support from Fujirebio Europe N.V. that provided the kits used for methylation analysis at no cost. Fujirebio Europe N.V. had no role in the design of the study, in the collection, analyses, or interpretation of data, in the writing of the manuscript, or in the decision to publish the results. Maria Benevolo has received non-financial support from Roche Diagnostics and Hologic S.r.L. and financial and non-financial support from Becton and Dickinson for work performed outside the range of the current study. The other authors declare no conflicts of interest.
