Del Mistro, Annarosa
Mancuso, Pamela
Carozzi, Francesca
De Marco, Laura
Bisanzi, Simonetta
Pompeo, Giampaolo
Ronco, Guglielmo
Gori, Silvia
Allia, Elena
Gustinucci, Daniela
Frayle, Helena
Iossa, Anna
Cesarini, Elena
Bulletti, Simonetta
Passamonti, Basilio
Viti, Jessica
Toniolo, Laura
Venturelli, Francesco
Giorgi Rossi, Paolo
Benevolo, Maria
,
Article History
Received: 4 July 2025
Accepted: 3 November 2025
First Online: 20 November 2025
Declarations
:
: The NTCC2 study protocol was approved by the S. Giovanni Battista University Hospital, Turin, Italy, on 20 June 2012 (N. CEI513) and by the local committees of all recruiting centers. The present extension of the study protocol was approved by the Comitato Etico Centrale IRCCS Lazio, Fondazione G.B. Bietti, N 1153/18, 20/11/2018. Informed consent was obtained from all individual participants included in the study.
: Maria Benevolo, as principal investigator, and Paolo Giorgi Rossi, as former principal investigator of the NTCC2 study, report nonfinancial support from Roche Diagnostics and Hologic S.r.l., which provided part of the reagents for free or at reduced price. Moreover, Maria Benevolo, Paolo Giorgi Rossi, Simonetta Bisanzi, and Laura De Marco obtained financial and non-financial support from Becton&Dickinson for genotyping NTCC2 stored samples. The manufacturers did not influence the study design, conduction, or data analysis. All other authors declare no conflict of interest.