Brunet, Jennifer https://orcid.org/0000-0003-3242-5444
Hussien, Julia https://orcid.org/0000-0001-7434-228X
Pitman, Anne
Wurz, Amanda https://orcid.org/0000-0002-7804-9811
Conte, Ellen https://orcid.org/0000-0002-1969-1118
Herry, Christophe https://orcid.org/0000-0003-1863-5920
Polskaia, Nadia https://orcid.org/0009-0003-2069-7626
Seely, Andrew https://orcid.org/0000-0002-6459-8801
Seely, Dugald https://orcid.org/0000-0003-4893-5254
Funding for this research was provided by:
Canadian CAM Research Fund
Article History
Received: 23 March 2026
Accepted: 28 July 2026
First Online: 5 August 2026
Declarations
Ethics approval and consent to participate: Approval was granted by the University of Ottawa (no.: H01-17-04, March 17, 2017) and the Canadian College of Naturopathic Medicine (no.: CCNMREB016, February 28, 2017). Written informed consent was obtained from all participants prior to their participation.
Consent for publication: Informed consent was obtained from all participants for results to be published.
Competing interests: Jennifer Brunet (corresponding author) reports financial support was provided by Canadian CAM Research Fund. While declared for transparency, the provision of financial support did not influence the research results, methodology, or interpretation. Andrew Seely from the Ottawa Hospital Research Institute (OHRI) is a patent holder, Founder/CEO, and shareholder of Therapeutic Monitoring Systems (TMS) Inc.—a company focused on commercialization of variability-derived clinical decisions support tools developed in OHRI’s Dynamical Analysis Laboratory. Christophe Herry is one of the inventors related to this patent. Neither A. Seely nor C. Herry report any conflict of interest directly related to the subject matter of this manuscript. Remaining co-authors declare no financial interests/personal relationships that may be considered as potential competing interests.