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Article History

Received: 26 January 2023

Accepted: 22 March 2023

First Online: 25 March 2023

Declarations

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: All procedures described in this study were performed in accordance with the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) (). This study was also carried out in strict accordance with recommendations in the Guidelines for Care and Use of Nonhuman Primates Version 2 and 3 of the Primate Research Institute, Kyoto University. This guideline was prepared based on the provisions of the Guidelines for Proper Conduct of Animal Experiments (June 1, 2006; Science Council of Japan), Basic Policies for the Conduct of Animal Experiments in Research Institutions under the Jurisdiction of the Ministry of Health, Labor and Welfare (effective on June 1, 2006; Ministry of Health, Labor and Welfare (MHLW)), Fundamental Guidelines for Proper Conduct of Animal Experiment and Related Activities in Academic Research Institutions (Notice No. 71 of the Ministry of Education, Culture, Sports, Science and Technology (MEXT) dated June 1, 2006), and Standards Relating to the Care and Management of Laboratory Animals and Relief of Pain (Notice No. 88 of the Ministry of the Environment dated April 28, 2006). The experiments were approved by the Animal Welfare and Animal Care Committee of the Primate Research Institute, Kyoto University (2010-066, 2011-093, 2012-047). All the experiments in this study were also performed in accordance with the guidelines of The University of Tokyo.

: Not applicable.

: The authors declare that they have no competing interests.